Endoform-Myriad

Endoform™ products:

• Provide a natural porous ECM bioscaffold for rapid cell infiltration
• Contain more than 150 ECM proteins known to be important in wound healing
• Contain residual vascular channels to support the establishment of new vasculature
• Can indicate the presence or absence of proteases and help restore protease balance and guide re-application
• Can be used by any wound care provider from day 1

Endoform™ Antimicrobial Restorative Bioscaffold contains 0.3% ionic silver, appropriate for use in early acute and chronic wound management where there is an elevated risk of infection.

• Provides broad spectrum antimicrobial activity for up to 7 days*
• Prevents biofilm formation
• Is non-cytotoxic to dermal cells

^{*Endoform™ Antimicrobial contains 0.3% ionic silver to protect the dressing from microbial colonization}

^{Ionic silver has been included in Endoform™ Antimicrobial to protect the device from microbial contamination. Reduction in colonization or microbial growth on the device has not been shown to correlate with a reduction in infections in patients. Clinical studies to evaluate reduction in infection have not been performed.}

Endoform™ products are made from AROA ECM™ technology and contain more than 150 extracellular matrix (ECM) proteins that enable it to interact with patient’s cells throughout all phases of healing.^{(1, 2)} Endoform™ products are 85% collagen and 15% important secondary molecules, including structural and adhesion proteins, and glycosaminoglycans (GAGs).⁽¹⁾ Endoform™ products only contain components found in tissue extracellular matrix.

During the inflammatory phase, chronic wounds are characterized by elevated wound proteases that limit healing by digesting important dermal proteins.⁽³⁾ Endoform™ products can help indicate the presence or absence of proteases and restores protease balance.^{(4, 5)}  If Endoform™ products are not visible in the wound bed at the time of reapplication, this can indicate elevated wound protease activity. However, if Endoform™ is visible, this can indicate that protease balance has been restored.

Endoform™ products also contain residual vascular channels that facilitate the rapid establishment of a dense capillary network by supporting migrating endothelial cells to establish new vasculature and a robust blood supply to help build new tissue.⁽⁶⁾ This process is termed angioconduction.